Ketamine-Assisted Psychotherapy in Grand Cayman

Where Science Meets Soul

A Breakthrough in Mental Health Healing

At Infinite Mindcare, in partnership with Doctor’s Express, we provide a fresh path for those ready to move forward in a new way.

Ketamine-Assisted Psychotherapy (KAP) is a cutting-edge, evidence-based treatment that blends neuroscience with deep emotional healing—ideal for individuals seeking relief from persistent emotional suffering.

Now offering both Intramuscular (IM) ketamine and Ketamine Nasal Spray in a safe, therapeutically supported environment—crafted around the principles of “set and setting,” ensuring each client enters the experience feeling emotionally prepared, physically comfortable, and deeply supported.

Now Accepting Clients With:

  • Major Depressive Disorder (MDD)
  • Post-Traumatic Stress Disorder (PTSD)
  • Generalized Anxiety Disorder (GAD)
  • Eating Disorders (with concurrent outpatient care or nutritional support)
  • Obsessive Compulsive Disorder (OCD)

Why Choose Infinite Mindcare?

Safety First

In partnership with Doctor’s Express, all medical screenings and ketamine administration are performed under licensed supervision. Emergency preparedness and professional monitoring are in place at every session.

Science + Therapy =
True Transformation

We follow the MAPS and Johns Hopkins protocols, combining ketamine dosing with psychotherapy to maximize outcomes and reinforce behavioral change through neuroplasticity.

Therapist-Led &
Psychedelic-Certified

All sessions are facilitated by licensed, master’s-level therapists certified in psychedelic therapy—with deep experience in trauma, anxiety, depression, and soul-work.

Spiritually-Informed &
Soul-Centered

We hold space for non-ordinary states of consciousness and deep emotional insight—whether rooted in personal growth, spiritual reconnection, or inner peace.

Local Access,
Global Standard

We’re proud to offer world-class care right here in Grand Cayman—eliminating the need for expensive overseas travel for KAP.

What to Expect: Your KAP Journey

Healing hands artwork depicting ketamine therapy.

We offer two administration methods:

Option 1: Intramuscular (IM) Ketamine

  • A single injection into the shoulder muscle (deltoid) administered by a medical professional
  • Creates a more immersive, often inward experience
  • Typically administered in a reclined setting with eye shades and music
  • Your therapist remains present for the full session

Option 2: Ketamine Nasal Spray

  • A self-administered nasal spray, delivered in a healthcare setting

  • Your therapist remains present for the full session

  • With its gentle onset, the nasal spray invites clients to stay grounded and expressive—so that the tools of therapy aren’t just remembered, but felt and lived through the experience.

Both routes are paired with psychotherapy, preparation, and integration—the pillars of transformation.

The Full Protocol

1. Initial Screening

Determine your eligibility and readiness through a confidential intake process.

2. Medical Consultation

Partner physicians at Doctor’s Express ensure medical safety and dosing appropriateness.

3. Preparation Sessions

Your therapist will guide you in setting intentions, building safety tools, and emotionally preparing for the medicine session.

4. Ketamine-Assisted Psychotherapy Sessions

A licensed therapist trained in psychedelic-assisted therapy will be present the entire time, helping you feel safe, grounded, and emotionally supported.

5. Integration Therapy

Each session is followed by a therapeutic integration session to explore your experience, anchor insights, and apply lessons to your life.

6. Ongoing Support

We continue to track progress, adjust dosage/frequency if needed, and provide holistic tools to sustain your healing.

Abstract neural pathways illuminated, representing ketamine therapy.

Integration & Psychedelic Support

Have you had a psychedelic experience elsewhere and want to make meaning of it?

Planning to travel for a retreat or ceremony and want to prepare emotionally and mentally?

We offer psychedelic preparation and integration sessions, whether or not ketamine is involved.

Psychedelic experiences can be profound—but without integration, they risk becoming a distant dream rather than a transformational pivot in your life.

Our team helps you bring what you saw, felt, or realized into your relationships, your choices, and your healing journey.

What Ketamine Might Feel Like

Ketamine therapy: vibrant neural network regeneration.

Each person’s journey is unique. Common experiences include:

  • A sense of detachment or spaciousness

  • Visual imagery or dream-like sensations

  • Emotional release or unexpected clarity

  • Shifts in self-perception or time awareness

  • Deep peace, presence, or compassion

Some sessions are gentle, others profound. Your therapist stays with you the entire time, helping you navigate whatever arises.

Ketamine & Neuroplasticity: Rewiring the Brain

  • Ketamine enhances neuroplasticity—your brain’s ability to form new connections and break free from stuck patterns.

  • In plain terms: Ketamine helps your brain “unlearn” what’s not working and “relearn” healthier ways of thinking, feeling, and being.

  • This window of cognitive flexibility makes therapy more effective and healing more accessible.

Ketamine therapy: Colorful brain connectivity visualization.

Explore the Research

Peer-reviewed studies from institutions like Yale, Harvard, Johns Hopkins, and more—organized by condition (depression, anxiety, PTSD, suicidality, OCD, eating disorders, and substance use).

You’ll find accessible summaries, links to journal articles, and a downloadable client handout.

Eligibility & Important Disclaimer

Ketamine-Assisted Therapy is not for everyone. We prioritize safety and informed decision-making.

You may not be eligible if you:

  • Have a personal/family history of psychosis or schizophrenia
  • Are pregnant or breastfeeding
  • Have uncontrolled high blood pressure or serious cardiac issues
  • Are actively abusing alcohol or substances (you must be sober to participate in KAT)
  • Are experiencing immediate suicidal intent with a plan and means without stabilization
  • Cannot commit to therapy-based integration

Each case is reviewed individually with your wellbeing as our top priority.

Ready to Begin?

If you’ve been diagnosed with a qualifying condition and haven’t found relief through traditional treatments—this may be your next step.

Frequently Asked Questions (FAQ)

KAP combines ketamine with psychotherapy to support emotional processing, healing, and behavioral transformation.

Yes, after screening and medical review, we’ll determine the best method for your needs and goals.

  • Use case: Mental Health
    Dose & Setting: Low-dose IM, in a therapy session (awake)
    Purpose: Facilitates emotional processing and neural rewiring
  • Use case: Pain Management
    Dose & Setting: Moderate dose, possibly IV or IM
    Purpose: Reduces chronic or acute pain signals
  • Use case: Anesthesia
    Dose & Setting: High-dose, often IV, with sedation
    Purpose: Induces unconsciousness for surgery

Visual imagery and altered perception are common, clients remain conscious, reflective, and supported throughout.

The IM Protocol is 15 sessions in total. Most plans include 6 KAP sessions, with prep and integration therapy for each. We tailor based on your needs.

Yes, when used in a controlled clinical setting under medical and therapeutic supervision.

Yes. Integration therapy is required and essential to long-term benefit and emotional safety.

No treatment guarantees a cure—but KAP often catalyzes significant relief, insight, and sustainable behavior change.

No. Please arrange for a ride. You may feel groggy or emotionally tender post-session.

KAP is not yet covered by most Cayman insurance providers. Please contact us for transparent pricing and available packages.

Yes—most are mild and temporary, including:

  • Nausea
  • Dizziness or disorientation
  • Emotional vulnerability
  • Temporary increase in blood pressure
  • Fatigue or spaciness afterward

These usually resolve within 1–2 hours. You will be monitored throughout, and we are trained to manage discomfort compassionately and safely.

The Science Behind Ketamine-Assisted Therapy

Grounded in Research. Guided by Soul.

Ketamine-Assisted Psychotherapy (KAP) is supported by a growing body of clinical research from leading institutions worldwide. This page offers a curated selection of peer-reviewed studies to help you understand the evidence behind KAT.

https://maps.org/
https://www.psychedelicpassage.com
https://ketamineinstitute.co
https://www.askp.org/

Michael Pollan’s work–both the Netflix series and book “How to Change Your Mind”

More resources:

https://www.nature.com/articles/s41398-025-03255-0
Ketamine and suicidality review

https://pubmed.ncbi.nlm.nih.gov/29202655/
Adjunctive ketamine demonstrated a greater reduction in clinically significant suicidal ideation in depressed patients within 24 hours compared with midazolam, partially independently of antidepressant effect.

https://www.nature.com/articles/s41398-024-03033-4
Our study provides real-world evidence that patients with recurrent MDD who were prescribed ketamine experienced significant long-term decrease in suicidal ideation compared with patients who were prescribed other antidepressants, within 270 days following the prescription.

https://www.columbiapsychiatry.org/news/ketamine-rapidly-improves-cognitive-function-making-those-suicidal-crisis-less-likely-harm-themselves
Ketamine Rapidly Improves Cognitive Function Making Those in Suicidal Crisis Less Likely to Harm Themselves

https://adaa.org/learn-from-us/from-the-experts/blog-posts/consumer-professional/ketamine-rising-star-mental-health

https://news.harvard.edu/gazette/story/2024/11/rapid-relief-for-the-severely-depressed-theres-a-catch/

 

Depression & Treatment-Resistant Depression (TRD)

Clinical Effectiveness of Ketamine in Depression
A comprehensive review highlighting ketamine’s rapid antidepressant effects in individuals with TRD.
🔗 Read Study


Double-Blind, Placebo-Controlled Trial
Investigates the efficacy of intravenous ketamine as an adjunctive therapy in TRD.
🔗 Read Study​


Yale Medicine Overview
An accessible summary of ketamine’s role in treating depression.
🔗 Read Article​


Harvard Gazette Report
Discusses recent findings on ketamine’s effectiveness in depression treatment.
🔗 Read Article​

 

Anxiety Disorders

Ketamine for Social Anxiety Disorder: A Randomized, Placebo-Controlled Crossover Trial
🔗 Read Study​


Safety and Efficacy of Maintenance Ketamine Treatment in Patients with Treatment-Refractory Generalized Anxiety and Social Anxiety Disorders
🔗 Read Study​


Post-Traumatic Stress Disorder (PTSD)

The potential of ketamine for posttraumatic stress disorder: a review of clinical evidence
🔗 Read Study​

 

Eating Disorders

Ketamine as adjuvant treatment in eating disorders: an exploratory study of a case series and retrospective analysis
🔗 Read Study​

 

Obsessive-Compulsive Disorder (OCD)

Randomized Controlled Crossover Trial. A proof-of-concept study assessing ketamine’s impact on OCD symptoms.
🔗 Read Study​


Efficacy in Unmedicated Adults with OCD

Evaluates the efficacy of ketamine in a larger group of unmedicated OCD patients.
🔗 Read Study​ Biological Psychiatry Journal


Cognitive Control Predicts Symptom Alleviation. Explores behavioral measures as potential moderators of treatment response.
🔗 Read Study​ Biological Psychiatry Journal

 

Suicidality

Ketamine for Acute Suicidal Ideation. A large randomized controlled trial confirming ketamine’s rapid and efficient treatment of suicidal ideation.
🔗 Read Study​ BMJ


Rapid Remission of Severe Suicidal Ideation. Evaluates the efficacy of a single infusion of ketamine in inducing rapid remission of severe suicidal ideation.
🔗 Read Study​ BioMed Central


Systematic Review and Meta-Analysis. Investigates the efficacy of ketamine in rapidly reducing acute suicidal ideation in patients with major depressive disorder.
🔗 Read Study​SpringerOpen

 

Ketamine & Neuroplasticity

How Ketamine Helps the Brain “Unlearn and Relearn”

Ketamine’s rapid antidepressant and therapeutic effects are largely attributed to its ability to enhance neuroplasticity—the brain’s natural ability to reorganize itself, form new neural connections, and break free from rigid, maladaptive patterns of thought and behavior.

  1. Rapid Neuroplasticity Changes and Response to Intravenous Ketamine
    Summary: This RCT showed that ketamine-induced changes in neuroplasticity were directly associated with reductions in depressive symptoms in patients with treatment-resistant depression.
    🔗 Read Study (Nature Translational Psychiatry, 2023)

  2. Neuroplasticity as a Convergent Mechanism of Ketamine and Classical Psychedelics

    Summary: This review explores the overlapping neuroplastic effects of ketamine and psychedelics, highlighting how both promote dendritic growth, synaptic remodeling, and emotional learning.

    🔗 Read Study (Trends in Pharmacological Sciences, 2021)